The effectiveness of methylcobalamin in the complex treatment of diabetic peripheral neuropathy
Vol. 24 No. 3 (2019), ORIGINAL PAPERS
Vol. 24 No. 3 (2019)

The effectiveness of methylcobalamin in the complex treatment of diabetic peripheral neuropathy

ORIGINAL PAPERS
https://doi.org/10.31793/1680-1466.2019.24-3.223
Published September 20, 2019
L.K. Sokolova
ДУ «Інститут ендокринології та обміну речовин ім. В.П. Комісаренка НАМН України»
Yu.B. Belchina
ДУ «Інститут ендокринології та обміну речовин ім. В.П. Комісаренка НАМН України»
O.E. Ozeryanskaya
ДУ «Інститут ендокринології та обміну речовин ім. В.П. Комісаренка НАМН України»
S.A. Chervyakova
ДУ «Інститут ендокринології та обміну речовин ім. В.П. Комісаренка НАМН України»
M.D. Tronko
ДУ «Інститут ендокринології та обміну речовин ім. В.П. Комісаренка НАМН України»
pdf (Українська)

Keywords

diabetes mellitus, diabetic peripheral neuropathy, vitamin B12, diagnosis, treatment.

How to Cite

Sokolova, L., Belchina, Y., Ozeryanskaya, O., Chervyakova, S., & Tronko, M. (2019). The effectiveness of methylcobalamin in the complex treatment of diabetic peripheral neuropathy. Endokrynologia, 24(3), 223-227. https://doi.org/10.31793/1680-1466.2019.24-3.223
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Abstract

Diabetic neuropathy is the most common complication of diabetes, found in 30-90% of patients. The relevance of the study is due to the prevalence of diabetic neuropathy, as well as assessing the effectiveness of the use of methylated form of Vit B12 in the treatment of patients with diabetes. The aim of this study was to determine the effectiveness of methylcobalamin (Diacobal, Kusum Pharm) in the complex treatment of patients with diabetes complicated by diabetic peripheral neuropathy (DPN). Material and methods. The study was conducted by a simple open method. The Michigan Neuropathy Screening Instrument (MNSI), the Neurological Symptoms Score (NSS), the European Quality of Life Questionnaire (EQ‑5D) were used to screen and determine the severity of
symptoms of DPN. Neurological examination of patients included an assessment of various types of sensitivity (pain, tactile, vibrational, cold, heat, proprioceptive, pressure sensation). Blood levels of vitamin B12 (cyanocobalamin) were determined in all patients. Diacobal was added to the regimen of traditional treatment for DPN regardless of the levels of vitamin B12.

https://doi.org/10.31793/1680-1466.2019.24-3.223
pdf (Українська)

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