Possibilities of Doppler sonography in topical diagnosis of parathyroid adenomas

Abstract

The aim of the present study was to evaluate the diagnostic accuracy and imaging patterns of colour Doppler ultrasonography (CDUS) and compare it with grayscale  US, 99mTc methoxyisobutylisonitrile (MIBI) scans, and combined US and MIBI scans in the preoperative diagnosis of parathyroid adenomas in patients with primary  hyperparathyroidism. According to histopathology results, the sensitivity, specificity, and accuracy of MIBI and US scan were 98%, 94%, 91%, and 70%, and 85%,  respectively. The overall sensitivity and specificity of combined US and MIBI was 92% and 95% respectively. The overall sensitivity, specificity, and accuracy of CDUS in the  correct diagnosis of parathyroid adenoma were 91%, 95%, 92%, respectively. The same data obtained for combined grayscale US and MIBI. Combining CDUS with  grayscale is safe and accurate method for evaluation of parathyroid adenoma.