Sex differences of expression ERK in rat adrenal gland
Vol. 20 No. 4 (2015), ORIGINAL PAPERS
Vol. 20 No. 4 (2015)

Sex differences of expression ERK in rat adrenal gland

ORIGINAL PAPERS
Published December 20, 2015
N.I. Levchuk
State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism, Nat. Acad. of Med. Sci. of Ukraine»
O.S. Lukashenia
State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism, Nat. Acad. of Med. Sci. of Ukraine»
O.S. Mikosha
State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism, Nat. Acad. of Med. Sci. of Ukraine»
O.I. Kovzun
State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism, Nat. Acad. of Med. Sci. of Ukraine»
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Keywords

metandamide
ERK1
ERK2
adrenal glands
rats
sex difference

How to Cite

Levchuk, N., Lukashenia, O., Mikosha, O., & Kovzun, O. (2015). Sex differences of expression ERK in rat adrenal gland. Endokrynologia, 20(4), 706-709. Retrieved from https://endokrynologia.com.ua/index.php/journal/article/view/236
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Abstract

The expression level of ERK1 and ERK2, and the effect of various metanandamide concentrations on it in the adrenal gland tissue of female and male rats were  investigated in vitro. The different levels of ERK1 and ERK2 expression in the adrenocortical tissue of different sex rats were established: the expression level of ERK1  and ERK2 was significantly lower in the adrenal glands of female rats compared with the adrenocortical tissue of male rats. The higher levels of ERK2 expression was also  observed in female rats in contrast to ERK1. The observed difference may be due to the influence of sex hormones on synthetic processes in the cell. Metandamide did  not effect on the level of ERK1 and ERK2 expression in the adrenal tissue of different sex rats.  

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Copyright (c) 2015 SI ≪V.P. Komisarenko Institute of Endocrinology and Metabolism, Natl. Acad. Med. Sci. of Ukraine≫

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