Radionuclide diagnostic of hemodynamic disturbances in males with metabolic syndrome and type 2 diabetes mellitus

Abstract

Cardiovascular diseases are the most common pathology in the world, leading to disability of early death. Their development is closely associated with type 2 diabetes mellitus (T2DM), the prevalence of which currently has signs of a pandemic. Early diagnosis of vascular lesions of various organs and systems in men with T2DM makes it possible, under the condition of timely and adequate treatment, to prevent or slow down the development of cardiovascular events: heart attacks, strokes. The goal is to study the state of testicular, renal and cerebral blood flow in men with diabetes mellitus using the radionuclide method. Materials and methods. 80 male patients with T2DM, aged 30 to 65 years, were examined. Investigations of the state of blood flow in the lower extremities, kidneys, brain tissue and testicles were performed on a GCS‑301T scintillation tomographic gamma camera (Orizon STTE). Results. In the examined, similar changes in both testicles were observed in the form of slowing blood flow in the vessels of large, medium and small caliber, as well as an increase in the time of complete testicular blood flow. In the early stages of nephropathy in patients with diabetes mellitus, the blood flow to the capillaries slows down. A significant increase in cerebral blood flow time was found in patients with T2DM. Conclusion. In patients with T2DM, microangiopathy precedes the development of macroangiopathies and is diagnosed by radionuclide methods even before the onset of

clinical symptoms.