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Abstract
Aim is to determine the frequency of concomitant pathology in the extratumoral tissue of the thyroid gland in the presence of a benign or malignant tumor. Material and methods. A
retrospective study of the cohort of patients who had surgery for thyroid tumor. The frequency of presence of histological signs of pathological changes in the extratumoral thyroid tissue was analyzed, taking into account the age and sex of patients; the information of the level of TSH in the blood was used for a part of patients. The dynamics of pathological change accompanying carcinomas in the extratumoral tissue for the period 2001-2015 was analyzed. Results. The most common pathological changes in extratumoral thyroid tissue is chronic thyroiditis, which more often accompanies papillary carcinoma, less often follicular, and more rarely medullary carcinoma or follicular adenoma. In anaplastic carcinoma, chronic thyroiditis is 2 times less common than with papillary carcinoma, but concomitant multi-node goiter in the extratumoral tissue of patients with anaplastic carcinoma (as well as with papillary and follicular carcinoma present in the gland) is diagnosed 3-6 times more often than with follicular adenoma, differentiated or medullary carcinomas. At the same time, the frequency of focal infiltration of the thyroid tissue by lymphocytes, which is a sign of inflammation, does not differ in patients with various thyroid tumors. Over the last 15 years of follow-up, the number of patients with papillary carcinoma and chronic thyroiditis increased up to 2.4 times; the number of patients with follicular carcinoma with and
without concomitant thyroiditis remained constant, and the rate of increase in the number of patients with medullar carcinoma and patients with the latter associated with thyroiditis was the same. Conclusions. The frequency of pathological changes in the extratumorous tissue of the thyroid gland depends on the nature of the neoplasm, the sex and age of the patients.
References
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