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Abstract
The relationship between cardiac and cerebral pathology is of undoubted interest among doctors of various specialties, dynamically expanding. Objective — to identify the relationship between the mass of the left ventricular myocardium (MLVM) and heart rate variability (HRV) in patients with cerebral atherosclerosis (CA) of stage 1-3, including type 2 diabetes. Material and methods. 229 patients with 1st‑3rd degree CA were involved in a comprehensive clinical and instrumental study. Patients were divided into 2 groups: І — with CA of 1-2 degree (without IS — comparison group); II — a general group of patients after
an ischemic atherothrombotic stroke. Results. The compared groups were statistically significantly different in the thickness of the LV walls. Thus, the minimum thickness of the interventricular septum and the posterior wall of the left ventricle was in the group of patients with CA (1.18 and 1.17 times less, respectively, compared with the group of patients with IS). To identify the relationships, a correlation analysis was carried out with the calculation of the Spearman rank correlation coefficient. So, in the general group of patients who underwent IS, one inverse correlation was established between the parameters of MLVM and LF/HF% (r = –0.30), and in the group of patients without IS with CA 1-2 stages of communication were not established. Conclusion. In patients with cerebral atherosclerosis of the 1-2 degree and type 2 diabetes, the thickness of the interventricular septum and the posterior wall of the left ventricle is statistically significantly less, and the concentric non-dilatation type of left ventricular remodeling is statistically significantly more often compared with patients who underwent an atherothrombotic stroke, which primarily indicates the fact that a stroke alone is not a predictor of subsequent cardiovascular events. The presence of an inverse correlation between CML and the ratio of the sympathetic/parasympathetic HRV in post-stroke patients with type 2 diabetes and the absence of it in patients with initial manifestations of cerebral atherosclerosis and type 2 diabetes indicate more pronounced physiological
relationships and less pronounced autonomic autonomic nervous system after the onset of significant cardiovascular events in patients with manifestations of cerebral atherosclerosis.
References
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