Age-related peculiarities of the response of male rat reproductive system to letrozole
Vol. 20 No. 1 (2015), ORIGINAL PAPERS
Vol. 20 No. 1 (2015)

Age-related peculiarities of the response of male rat reproductive system to letrozole

ORIGINAL PAPERS
Published March 15, 2015
O.G. Reznikov
State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism, Natl Acad. Med. Sci. of Ukraine»
L.V. Chaikovska
State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism, Natl Acad. Med. Sci. of Ukraine»
L.I. Polyakova
State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism, Natl Acad. Med. Sci. of Ukraine»
O.V. Sachynsk
State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism, Natl Acad. Med. Sci. of Ukraine»
O.V. Yanishevsky
Farmak Joint-Stock Company
PDF (Українська)

Keywords

letrozole
prostate
testes
rats

How to Cite

Reznikov, O., Chaikovska, L., Polyakova, L., Sachynsk, O., & Yanishevsky, O. (2015). Age-related peculiarities of the response of male rat reproductive system to letrozole. Endokrynologia, 20(1), 425-430. Retrieved from https://endokrynologia.com.ua/index.php/journal/article/view/206
ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver

Download Citation

Endnote/Zotero/Mendeley (RIS) BibTeX

Abstract

The authors have studied the effects of letrozole (Letromara), a steroid aromatase inhibitor, at a dose of 1 mg/kg b.w. every other day during 14 days, on reproductive  organs of young and aging male rats. Letrozole stimulated androgen target organs in aging animals showing age-related involution of reproductive system and perhaps in young rats. Biological effects of androgen stimulation were noted despite the absence of an increase in plasma testosterone levels.

PDF (Українська)
Copyright (c) 2015 SI ≪V.P. Komisarenko Institute of Endocrinology and Metabolism, Natl. Acad. Med. Sci. of Ukraine≫

Downloads

Download data is not yet available.