Cardiac and vascular remodeling in patients with hypothyroidism, associated with hypertension

Abstract

The results of studying the peculiarities of changes in structural and hemodynamic indices of cardiovascular system in patients with hypothyroidism, associated with  hypertension (HT), evaluated by echocardiography and ultrasound duplex scanning of brachiocephalic vessels and arterial cerebral vessels of Viliziyev circuit (VC) are  demonstrated in this article. The examination was conducted in 46 patients with hypothyroidism associated with arterial hypertension, in 45 hypertensive patients  without thyroid disease, and in 29 control individuals with using the Phillips IE33 apparatus. The hypertrophy signs of the left atrium, asymmetric left ventricular  hypertrophy and remodeling of the vascular wall were revealed: disorders of elasticity, increase in the diameter, CIM thickening, reduction of the linear velocity in  blood flow simultaneously in 2 or 3 sections of the carotid arteries, the main arteries VC, in 80% of patients the atherosclerotic plaques were mostly with  heterogeneous structure. The established changes were more frequent and in greater volume in patients with hypothyroidism associated with arterial hypertension  comparing to patients only with hypertension.