The dynamics of echocardiographic parameters against a background of alpha-lipoic acid and zinc sulfate usages in postinfarction patients with type 2 di abetes mellitus

Abstract

The article presents data of echocardiographic examination of 44 patients with type 2 diabetes mellitus who had non-Q-myocardial infarction and their dynamics under the effect of
the 4-month combined treatment with alpha-lipoic acid and zinc sulfate. It was found a significant reduction in LA (p<0.05) and RA (p<0.05) cavities, a decrease of the maximum velocity of the peak of late diastolic filling — Va on tricuspid valve (p<0.05), deceleration time of early diastolic filling of RV — DT (p<0.05), significantly increased ratio of velocity of early and late peaks of diastolic filling (Vе/Vа) of RV (p<0.05), an increase of EF of LV (p <0.05) was also registered. A significant decrease of PA pressure (p<0.05) was revealed by the
examination of systolic blood flow from the output department of the RV. Thus, the 4-month use of alpha-lipoic acid and zinc sulfate in the complex treatment of patients with type 2 diabetes mellitus who had non-Q-myocardial infarction, improves relaxation and contractile function of the heart, causes atriums size reduction and reduces the average pressure in the LA.