Анотація
У статті представлено огляд літературних даних щодо метаболізму цинку в організмі людини та його ролі в розвитку цукрового діабету та ішемічної хвороби серця. Проаналізовано досвід клінічного застосування препаратів цинку.
Посилання
1. Prasad A.S. Zinc: role in immunity, oxidative stress and chronic inflammation // Curr. Opin. Clin. Nutr. Metab. Care. 2009, 12, N 6, 646-652.
2. Chasapis C.T., Loutsidou A.C., Spiliopoulou C.A. et al. Zinc and human health: an update // Arch. Toxicol. 2012, 86, 4, 521-534.
3. Foster M., Samman S. Zinc and redox signaling: perturbations associated with cardiovascular disease and diabetes mellitus // Antioxid. Redox Signal. 2010,
13, 10, 1549-1573.
4. Little P.J., Bhattacharya R., Moreyra A.E., Korichneva I.L. Zinc and cardiovascular disease // Nutrition. 2010, 26, 1050-1057.
5. Kelleher S.L., McCormick N.H., Velasquez V., Lopez V. Zinc in specialized secretory tissues: roles in the pancreas, prostate, and mammary gland // Adv. Nutr. 2011, 2, 101-111.
6. Haase H., Rink L. Zinc Signaling. Zinc in Human Health // Amsterdam, Netherlands: IOS Press. 2011. 243 p.
7. Kambe T. An overview of a wide range of functions of ZnT and Zip Zinc transporters in the secretory pathway // Biosci. Biotechnol. Biochem. 2011, 75, N 6, 1036-1043.
8. Maret W. New perspectives of Zinc coordination environments in proteins // J. Inorganic Biochem. 2011, 111, 110-116.
9. Beyersmann D., Haase H. Functions of Zinc in signaling, proliferation and differentiation of mammalian cells // BioMetals. 2001, 14, N 3-4, 331-341.
10. Scott D.A. Crystalline insulin // Biochem. J. 1934, 28, 1592-1602.
11. Chimienti F., Devergnas S., Favier A., Seve M. Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory
granule // Diabetes. 2004, 53, 2330-2337.
12. Coulston L., Dandona P. Insulin-like effect of Zinc on adipocytes // Diabetes. 1980, 29, N 8, 665-667.
13. May J.M., Contoreggi C.S. The mechanism of the insulin-like effects of ionic Zinc // J. Biol. Chem. 1982, 257, N 8, 4362-4368.
14. Ezaki O. IIb group metal ions (Zn2+, Cd2+, Hg2+) stimulate glucose transport activity by post-insulin receptor kinase mechanism in rat adipocytes // J. Biol.
Chem. 1989, 264, N 27,16118-16122.
15. Tang X.H., Shay N.F. Zinc has an insulin-like effect on glucose transport mediated by phosphoinositol-3-kinase and Akt in 3T3-L1 fibroblasts and adipocytes // J.
Nutrit. 2001, 131, N 5, 1414-1420.
2. Chasapis C.T., Loutsidou A.C., Spiliopoulou C.A. et al. Zinc and human health: an update // Arch. Toxicol. 2012, 86, 4, 521-534.
3. Foster M., Samman S. Zinc and redox signaling: perturbations associated with cardiovascular disease and diabetes mellitus // Antioxid. Redox Signal. 2010,
13, 10, 1549-1573.
4. Little P.J., Bhattacharya R., Moreyra A.E., Korichneva I.L. Zinc and cardiovascular disease // Nutrition. 2010, 26, 1050-1057.
5. Kelleher S.L., McCormick N.H., Velasquez V., Lopez V. Zinc in specialized secretory tissues: roles in the pancreas, prostate, and mammary gland // Adv. Nutr. 2011, 2, 101-111.
6. Haase H., Rink L. Zinc Signaling. Zinc in Human Health // Amsterdam, Netherlands: IOS Press. 2011. 243 p.
7. Kambe T. An overview of a wide range of functions of ZnT and Zip Zinc transporters in the secretory pathway // Biosci. Biotechnol. Biochem. 2011, 75, N 6, 1036-1043.
8. Maret W. New perspectives of Zinc coordination environments in proteins // J. Inorganic Biochem. 2011, 111, 110-116.
9. Beyersmann D., Haase H. Functions of Zinc in signaling, proliferation and differentiation of mammalian cells // BioMetals. 2001, 14, N 3-4, 331-341.
10. Scott D.A. Crystalline insulin // Biochem. J. 1934, 28, 1592-1602.
11. Chimienti F., Devergnas S., Favier A., Seve M. Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory
granule // Diabetes. 2004, 53, 2330-2337.
12. Coulston L., Dandona P. Insulin-like effect of Zinc on adipocytes // Diabetes. 1980, 29, N 8, 665-667.
13. May J.M., Contoreggi C.S. The mechanism of the insulin-like effects of ionic Zinc // J. Biol. Chem. 1982, 257, N 8, 4362-4368.
14. Ezaki O. IIb group metal ions (Zn2+, Cd2+, Hg2+) stimulate glucose transport activity by post-insulin receptor kinase mechanism in rat adipocytes // J. Biol.
Chem. 1989, 264, N 27,16118-16122.
15. Tang X.H., Shay N.F. Zinc has an insulin-like effect on glucose transport mediated by phosphoinositol-3-kinase and Akt in 3T3-L1 fibroblasts and adipocytes // J.
Nutrit. 2001, 131, N 5, 1414-1420.
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